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In molecular biology, the jacalin-like lectin domain is a mannose-binding lectin domain with a beta-prism fold consisting of three 4-stranded beta-sheets, with an internal pseudo 3-fold symmetry. Some lectins in this group stimulate distinct T- and B-cell functions, such as Jacalin, which binds to the T-antigen and acts as an agglutinin. This domain is found in 1 to 6 copies in lectins. The domain is also found in the salt-stress induced protein from rice and an animal prostatic spermine-binding protein. Database of jacalin like lectins and structure function relations.〔Raval et al, "A database analysis of jacalin-like lectins: sequence–structure–function relationships" Glycobiology vol. 14 no. 12 pp. 1247–1263, 2004 http://glycob.oxfordjournals.org/content/14/12/1247.full.pdf〕 Proteins containing this domain include: *Jacalin, a tetrameric plant seed lectin and agglutinin from ''Artocarpus heterophyllus'' (jackfruit), which is specific for galactose. *Artocarpin, a tetrameric plant seed lectin from ''A. heterophyllus''. *Lectin MPA, a tetrameric plant seed lectin and agglutinin from ''Maclura pomifera'' (Osage orange). *Heltuba lectin, a plant seed lectin and agglutinin from ''Helianthus tuberosus'' (Jerusalem artichoke). *Agglutinin from ''Calystegia sepium'' (Hedge bindweed). *Griffithsin, an anti-viral lectin from red algae (''Griffithsia'' species). ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Jacalin-like lectin domain」の詳細全文を読む スポンサード リンク
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